Research Articles
Atomistic vs. Coarse-Grained Models: A Strategic Guide for Biomedical Simulation
This article provides a comprehensive comparison of atomistic and coarse-grained potential models for researchers and professionals in computational biology and drug development.
Chemical Probes in Target Validation: A Comprehensive Guide for Robust Biomedical Research
This article provides a comprehensive guide for researchers and drug development professionals on the use of high-quality chemical probes for biological target validation.
Benchmarking Global Optimization Algorithms: Performance Comparisons for Scientific and Drug Discovery Research
This article provides a comprehensive, comparative analysis of global optimization algorithms, tailored for researchers and professionals in drug development and life sciences.
HILIC-UPLC for Glycan Analysis: A Comprehensive Comparison with LC-MS, CE-LIF, and Other Key Methods
This article provides a critical evaluation of Hydrophilic Interaction Liquid Chromatography-Ultra Performance Liquid Chromatography (HILIC-UPLC) alongside other prominent techniques for glycan analysis, including capillary electrophoresis-laser induced fluorescence (CE-LIF), mass spectrometry...
Comparative Analysis of Glycomics Methodologies: From Foundational Principles to Advanced Applications in Biomedicine
This article provides a comprehensive comparative analysis of modern glycomics methodologies, tailored for researchers, scientists, and drug development professionals.
Chemical Probe Validation for Target Engagement: A Comprehensive Guide for Robust Biomedical Research
This article provides a comprehensive guide for researchers and drug development professionals on the critical process of chemical probe validation for target engagement.
Multi-Step Sample Preparation Quality Control: A Comprehensive Guide for Robust Analytical Results
This article provides a systematic framework for implementing quality control (QC) in multi-step sample preparation, a critical determinant of success in biomedical and clinical research.
Chemical Probe Target Validation: Best Practices for Reliable Research and Drug Discovery
This article provides a comprehensive guide to the rigorous validation of chemical probes, essential tools for target identification and phenotypic screening in biomedical research.
Particle Swarm Optimization for Molecular Clusters: A Comprehensive Guide for Drug Discovery and Materials Design
This article provides a comprehensive exploration of Particle Swarm Optimization (PSO) for predicting the structure and properties of molecular clusters, a critical task in drug discovery and materials science.
Basin-Hopping Algorithm: A Complete Guide to Mapping Potential Energy Surfaces for Drug Discovery
This comprehensive guide explores the basin-hopping algorithm for mapping complex potential energy surfaces (PES), with direct applications in computational drug discovery and materials science.