Discover how IGF-I stimulates the xC- amino acid transporter to reduce intracellular ROS levels and promote breast cancer cell proliferation.
Explore how computational approaches are transforming cancer drug discovery through AI, molecular modeling, and advanced simulations.
Explore how 3D microscale niches are transforming cancer research by providing realistic models of tumor angiogenesis and enabling personalized treatment approaches.
Discover how cancers develop resistance to irreversible EGFR inhibitors through the IGF-1R pathway and the promising combination therapies being developed.
Scientists use digital avatars of cancer to uncover how glucose scarcity can ironically make tumours more invasive.
Explore how chemical biology is transforming our understanding of cancer drug resistance and developing innovative strategies to overcome it.
Discover how scientists are using fucose-truncated Ipomoeassin F analogues to disrupt cancer cell protein transport and develop innovative cancer treatments.
New research reveals EGFR and HER2 are quantitatively equal partners in driving breast cancer signaling, with implications for combination therapies.
Breakthroughs in immunotherapy, mRNA technology, and precision targeting are ushering in an era where universal cancer vaccines could render tumors vulnerable to the body's own immune cells.
Exploring how BET proteins and bromodomain inhibitors are transforming cancer therapy through epigenetic regulation.